Monthly Archives: April 2015

Bought EPO and now Regret It

This entry was posted in Important Life Stories on by .

That’s right.  I would have bet almost anything that I would never have a reason to actually purchase Epogen (EPO).  But I would have lost that bet.

I know the title is a little misleading. I am getting it for my dog, Bromont.

Bromont has been really slow recently.   That is to be expected with terminal HSA cancer.  But his gums are whitish and obviously he is low on red cells.  So we took him in for a blood test today and his hematocrit was 15.2%  It was 27 two week ago, and 38, 2 weeks before that.  The normal range is 37-62.  So, his is less than half of normal.  His red count is less than half of low also.

There are a couple reasons that could cause this.   His red cell production could be suppressed in the marrow due to cytokines stimulated by the tumor, microangiopathic destruction of red blood cells as they pass through the tumors.  Or, he has chronic bleeding.   Or, I guess, both.

So, I got on this kick that he isn’t comfortable and that he needs more oxygen, thus red cells.  After doing some a little research, perhaps not enough, I thought that maybe EPO would be of benefit to him.

So, I researched that a little more, along with my vet from K-State.  It is kind of crazy.  a 3000 U/ml vial of 10ml that cost $30 in the mid 90’s now costs $1500 at Walgreens.  But a 2000 U/ml vial, same size is $359.  So 1 1/2 times the dosage, which makes it 1/3 of the cost.  (FYI, a 20000 U/ml vial is $8700.  I’m not sure how much a human needs, but the stuff is pretty expensive.  At least at Walgreens.)

Anyway, when Bromont went to get the blood test, we got 1 ml to start.  I gave that to him yesterday.

It was pretty weird holding that little vial of water-like liquid in my hands.  It contained the substance of what could be the difference between a mediocre athlete and a Tour de France winner.  Just a little clear liquid, that isn’t all that hard to obtain.   It all seems so silly.  It seems so wrong.  It was creepy.

After doing all this, I spent more time and did a lot more research and I’m of the opinion that it won’t help.  I don’t think that any amount of EPO is going to enable him to make the appropriate amount of red cells to stay somewhat healthy.  I’ve already special ordered the EPO from the pharmacy, so I hope they don’t make me take it. Thus, the regret.

So, I decided on a blood transfusion route now.  This morning, we’re taking him to K-State to get a 5 hour blood transfusion.  In theory, it will double his hematocrit.  I don’t think there is any way to know how long that will last.  In kind of depends on why he doesn’t have any now.  His levels dropped from 27 to 15 in two weeks.  I guess the best we could hope for is the same again.

I didn’t have any idea if they happen to have a bunch of dog blood sitting around.  His type even.  Sounds like they do.  I wonder where they get that?

I’m not trying to play God or anything with my dog.  I’m just trying to make him as comfortable as possible through all of this.  If this makes him feel better, then I’m all for it.  I’m a little torn about having him at the vet school for 5 hours, but hopefully I can sit with him the whole time while he gets the blood.

This whole process is a learning experience.  What I’ve learned so far is that you don’t have any idea where you are in the process.  If you would have asked me two weeks ago, on any given day, whether he would still be alive two weeks later, I might have answered, 100% no, or 100% yes, just depending on what hour of the day the question was asked.

My vet, who is an avid cyclist, told me he would keep it quiet that I got EPO for my dog.  He said next thing you know, I’d be getting it for my grandmother, etc.  It is so weird that the only reason I know of this drug is because of the abuse of it in our sport.  I really thought that Hemopure would be the perfect drug for Bromont.  Wow, now that I looked that link up, I see that it was approved for canine use in 1998.  I wonder about the availability of that?  It might be better than a transfusion.

Anyway, Bromont seems happy enough.  He likes to go for car rides.  He loves sleeping with us.  Every once in a while he plays a little still.  He likes to take walks, but not very far.  He is a pretty picky about food, but he always was.   I love the dog to death and feel obligated to do everything in my power to help him feel as good as possible as long as possible.  It’s as simple as that.

Here is a vial of the drug of choice for endurance athletes the last two decades or so.  It seemed so weird even holding it.

Here is a vial of the drug of choice for endurance athletes the last two decades or so. It seemed so weird even holding it.

This blood test was very depressing.  His blood is total shit.  I hope I can do something to make him feel a little better for a short time.

This blood test was very depressing. His blood is total shit. I hope I can do something to make him feel a little better for a short time.

 

 

  

Bromont on his way for some new blood. 

Headaches

This entry was posted in Just Life on by .

I’ve woke up the last two morning with a pretty serious headache.  I don’t get headaches much and feel really sorry for anyone that gets them often.

I’m pretty sure I know the reason.  It’s probably from drinking too much red wine before going to bed.  I don’t drink much and if I drink right before going to bed I shouldn’t be surprised when I wake up with a headache.

I’m not sure why I do it when I know the consequences.  I guess I don’t take the next morning into consideration the night before.

The last couple days haven’t been all that great.

First, Bromont isn’t doing very well.  Actually, he’s doing pretty badly. I was hoping that he would feel better after getting some new red blood cells, but it didn’t seem to help him at all.

Nothing seems to go right when I’m dwelling on Bromont.  I decided I should do some manual labor to take my mind off of him, so I went to a rental center to get a big trailer to haul a bunch of vegetation.  It took forever for a new girl at the rental place to check me out.  I went around to get the trailer and the wire for the 4 hole light hookup wouldn’t reach to my tow hitch eletrical.  I have a 7 prong outlet and had bought a adaptor to allow a 4 hole plug to work.  The guys that were hooking it up said they would look for an extention to connect the 3 feet.

They came back and said I had to buy one from them for $10.  I told they I wouldn’t.  Seems like that should be part of the rental.  They sent me inside.  Inside, I talked to the owner.  He told me that “they” used to loan them, but that no one returned them, so “they” just started selling them.  I told him I’d return it and that if I didn’t they could just take it from the deposit.  He said no, that isn’t how they do it anymore.  I asked him why he was using the word they?  I knew he owned the business.  He didn’t answer.  I figured I’d go to an auto parts store and buy one.  I didn’t want to give they guys my money.  So I left.

The owner followed me out and said that he didn’t think the trailer was going to work and proceeded to disconnect it.  I didn’t say a word to him, just let him proceed.  What a prick.   I am never rented any tools there again, and I rent a fair amount of tools.

So, I used a small trailer I have.  I had to mince the stuff, with a chainsaw, to fit it all into the smaller trailer, but did, which was the highlight of the day.  I guess I saved $75, but it was a lot more work.

I decided to go for a ride after that.  I got 4 miles from my house and flatted on some glass.  Then I proceeded to try to fix it with, what it seems now, two flat tubes.  I had to ride home on the flat.  I just left my bike in the garage, not messing with it.  I hope I didn’t hurt the rim much.

So then, I decided to go mow.  This was at about 7 pm and it gets dark here a little after 8.  Plus, it was supposed to start raining anytime.  I got done mowing two places and then went down to the building.  No one, me or Kris, hadn’t mowed there yet.  There were a fair amount of leaves, plus Sycamore balls, or pollen, or whatever you call it, all over.

It was like mowing in a dust bowl.  Dry leaves, pollen, etc. everywhere.  It was a mess and I could barely breathe.  About 1/2 way through, the mower quit working.  It was dark by then.  I took it over under the light and it looked like the gas tank, which is metal, had broken off the mower.  Something that I couldn’t fix quickly.  So, a half complete job.  I hate leaving a lawn half mowed.  It is like shoveling  half a driveway.  It must be something in my mind, but it drives me nuts.

I’m over it this morning.  It rained all night, pretty hard, so I’m not finishing it today anyway.

There are lots of places I’d rather be right now.  There are at least three different races, Joe Martin, which is just down the street, The Whiskey 50 MTB race and the Belgian Waffle Ride, North of San Diego, that I’d like to be doing this weekend.  But, I’m home.

It is pretty stressful taking care of a dying animal.  Especially a dog that has been with you for a long time.  I can’t think of many things worse to do.  But, I can’t imagine doing anything else.  It is exactly where I’m supposed to be, no matter how much tension it causes.  We are best friends and it is my place to help him through this.

I do hope today goes a little smoother though.

I know this doesn't have anything to do with this post, but I was stunned by how shitty the bikes were, at every bike rack, on the K-State campus.  I had no idea this was the case.

I know this doesn’t have anything to do with this post, but I was stunned by how shitty the bikes were, at every bike rack, on the K-State campus. I had no idea this was the case.