The is an article at Cycling Today about a study at The University of Kent that had results that said that taking acetaminophen decreased times in 10 mile time trials by 30 seconds. That is a pretty large number.
The results of this study and one other, said that the acetaminophen reduces pain and allows the rider to hold a higher exertion level at higher temperatures. That is an interesting part. Higher output at higher temperatures.
I think there needs to be a larger study group. The first study had only 13 riders and the 2nd, repeat study, had 11. These guys were riding around a 26 minute time, so they were super great cyclists. But still, the results were amazing.
I heard a podcast about the effects of over dosing Tylenol/acetaminophen and it is ugly. Especially in children. Too much and it does severe liver damage. Not a very good drug to be taking when dehydration is common occurence.
Anyway, it is interesting. Funny how a normal pain relieve, over the counter, anti-inflammatory can be used as a “doping” product. Funny, as in strange, not funny as humorous.